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| Progress of Research on Organic Fibrosis with TraditionalChinese Medicine |
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| DOI：10.15806/j.issn.2311-8571.2015.0038 |
| KeyWord:Organic fibrosis, traditional Chinese medicine (TCM), clinical efficacy, Fuzheng Huayu recipe |
| Author | Institution |
| Qing-Lan Wanga |
a.E-Institute of Shanghai Municipal Education Committee, Shanghai University of Traditional Chinese Medicine, Shanghai, China |
| Xiao-Ning Wanga |
a.E-Institute of Shanghai Municipal Education Committee, Shanghai University of Traditional Chinese Medicine, Shanghai, China |
| Ping Liuab* |
a.E-Institute of Shanghai Municipal Education Committee, Shanghai University of Traditional Chinese Medicine, Shanghai, China
b.Institute of Liver Diseases, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China |
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| Abstract: |
| Fibrosis is the remodeling and repair processes of chronic injuries. There are few effective therapies. Chinese medicine formula, the main
pattern of traditional Chinese medicine (TCM) in clinic, applies a multi-component, multi-target and complicated approach in the treatment
of diseases, and certainly shows good comprehensive therapeutic effects on fibrosis. In this review, the clinical study, effects and mechanism of
action of Fuzheng Huayu recipe in the treatment of liver, pulmonary, and renal fibrosis was analyzed and evaluated. Meanwhile, based on the
understanding of TCM pathogenesis for liver cirrhosis, this review will also briefly introduce the research of different classical Chinese
medicine formulae with various functions in the treatment of experimental liver fibrosis induced by different methods, including comparing
the efficacy, analyzing the action characteristics and mechanism of effective formulae, exploring pathological and biological basis of TCM
diagnostic and therapeutic pattern, which will contribute to the research of TCM in the treatment of organ fibrosis. |
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