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| Potential Role of EGF and EGFR in TongueCoating Formation |
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| DOI：10.15806/j.issn.2311-8571.2016.0020 |
| KeyWord:Tongue coating, epidermal growth factor, epidermal growth factor receptor, review |
| Author | Institution |
| Yi-Shuang Tanga |
a.Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai ,China |
| Yu Zhaoa |
a.Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai ,China |
| Jing-Hua Penga* |
a.Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai ,China |
| Yi-Yang Huab* |
a.Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai , China
b.Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Key Laboratory of Liver and Kidney Diseases, Ministry of Education,Shanghai , China |
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| Abstract: |
| Tongue coating, as a sensitive index of the physiological and pathological changes of human organs, is an important basis for the Traditional
Chinese Medicine (TCM) syndrome differentiation and treatment. Mechanism of the formation and change of tongue coating is an important
scientific problem. In recent years, researches indicated that in addition to apoptosis related genes, epidermal growth factor (EGF) and
epidermal growth factor receptor (EGFR) also contribute to tongue coating formation. In this paper, we summarized recent studies on the
potential role of EGF and EGFR in regulating the formation of tongue coating to provide some reference for the further investigations on
tongue coating formation mechanisms. |
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