|
| Systems biology of resilience and optimal health:integrating Chinese and Western medicine pe8rspectives |
| |
| View Full Text View/Add Comment Download reader |
| DOI：10.15806/j.issn.2311-8571.2016.0024 |
| KeyWord:Health, Wellness, Resilience, Systems biology, Chinese diagnosis |
| Author | Institution |
| Herman van WietmarschenBing Zhuabc* |
a.TNO The Netherlands Organization for Applied Scientific Research, Utrechtseweg 48, 3704 HE Zeist, The Netherlands
b.Sino Dutch centre for Preventive and personalized Medicine, Utrechtseweg 48, 3704 HE, Zeist, the Netherlands
c.Louis Bolk Institute, Hoofdstraat 24, 3972 LA Driebergen-Rijsenburg, The Netherlands |
| Yan Schroënb |
b.Sino Dutch centre for Preventive and personalized Medicine, Utrechtseweg 48, 3704 HE, Zeist, the Netherlands |
| Victor Kalla |
a.TNO The Netherlands Organization for Applied Scientific Research, Utrechtseweg 48, 3704 HE Zeist, The Netherlands |
| Marvin Steijaertd |
d.Open Analytics, Jupiterstraat 20, 2600 Antwerpen, Belgium |
| Albert A. de Graafa |
a.TNO The Netherlands Organization for Applied Scientific Research, Utrechtseweg 48, 3704 HE Zeist, The Netherlands |
| Ben van Ommena |
a.TNO The Netherlands Organization for Applied Scientific Research, Utrechtseweg 48, 3704 HE Zeist, The Netherlands |
| Jan van der Greefab |
a.TNO The Netherlands Organization for Applied Scientific Research, Utrechtseweg 48, 3704 HE Zeist, The Netherlands
b.Sino Dutch centre for Preventive and personalized Medicine, Utrechtseweg 48, 3704 HE, Zeist, the Netherlands |
|
| Hits: 1667 |
| Download times: 1873 |
| Abstract: |
| Western science has been strong in measuring details of biological systems such as gene expression levels and metabolite concentrations, and
has generally followed a bottom up approach with regard to explaining biological phenomena. Chinese medicine in contrast has evolved as a
top down approach in which body and mind is seen as a whole, a phenomenological approach based on the organization and dynamics of
symptom patterns. Western and Chinese perspectives are developing towards a ‘middle out’ approach. Chinese medicine diagnosis, we will
argue, allows bridging the gap between biologists and psychologists and offers new opportunities for the development of health monitoring
tools and health promotion strategies.
In this paper, health, resilience and stress concepts are explored from an integrated systems biology perspective. This is followed by a discussion
about measuring aspects of health and resilience. Then the issue of how to integrate different types of data is discussed. Semi-quantitative
modeling appears to be very suitable and looks promising for building integrated health models. The challenge for the future lies in applying those
models in developing personalized health monitoring and advice systems that will tempt people to lead more healthy lives. |
| Close |
|
|
|