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| Metabolomics Deciphering Therapeutic Effects andMechanism of Traditional Chinese Medicines |
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| DOI：10.15806/j.issn.2311-8571.2016.0027 |
| KeyWord:Metabolomics, Biomarkers, Metabolites, Traditional Chinese medicine, Syndromes |
| Author | Institution |
| Wei-Wei Maab |
a.National TCM Key Laboratory of Serum Pharmacochemistry, Sino-America Chinmedomics Technology Cooperation Center,Research Center of Chinmedomics State Administration of TCM, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese
Medicine, Heping Road 24, Harbin , China.
b.School of Pharmacy, Heilongjiang University of Chinese Medicine, Heping Road, Harbin, China. |
| Ai-Hua Zhanga |
a.National TCM Key Laboratory of Serum Pharmacochemistry, Sino-America Chinmedomics Technology Cooperation Center,Research Center of Chinmedomics State Administration of TCM, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese
Medicine, Heping Road 24, Harbin , China. |
| Hui Suna |
a.National TCM Key Laboratory of Serum Pharmacochemistry, Sino-America Chinmedomics Technology Cooperation Center,Research Center of Chinmedomics State Administration of TCM, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese
Medicine, Heping Road 24, Harbin , China. |
| Xiang-Cai Menga |
a.National TCM Key Laboratory of Serum Pharmacochemistry, Sino-America Chinmedomics Technology Cooperation Center,Research Center of Chinmedomics State Administration of TCM, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese
Medicine, Heping Road 24, Harbin , China. |
| Xi-Jun Wanga* |
a.National TCM Key Laboratory of Serum Pharmacochemistry, Sino-America Chinmedomics Technology Cooperation Center,Research Center of Chinmedomics State Administration of TCM, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese
Medicine, Heping Road 24, Harbin , China. |
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| Abstract: |
| Traditional Chinese medicine (TCM), an ancient medical system, has the advantages of multi-targeting and multi-ingredient preparations, and
is different from modern pharmacology. However, because of the complexity of TCM and the limitation of present investigation method, the
research for deciphering the scientific basis and systematic features of TCM is difficult to go further. Metabolomics has a significant increased
study in recent years and enables mapping of early biochemical changes in disease and hence provides an opportunity to develop predictive
biomarkers. Moreover, its method and design resemble those of traditional Chinese medicine. Therefore, it can provide useful tools for
exploring essence of TCM, and will help to in-depth understand Chinese medicine syndromes. In this mini-paper, particular attention will be
paid to the past successes in applications of robust metabolomics to contribute to small metabolites discovery in TCM development. |
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