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| Interactions Between Traditional Chinese Medicine andAnticancer Drugs in Chemotherapy |
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| DOI：10.4103/wjtcm.wjtcm_6_17 |
| KeyWord:Anticancer, interactions, natural compounds, traditional Chinese medicine, traditional Chinese medicine formulae |
| Author | Institution |
| Zhi‑Jie Dingab |
a.School of Pharmacy, Shanghai University of Traditional Chinese Medicine, b.Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery,
Shanghai , China |
| Dan‑Qing Xuab |
a.School of Pharmacy, Shanghai University of Traditional Chinese Medicine, b.Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery,
Shanghai , China |
| Yuan‑Zhi Laoab |
a.School of Pharmacy, Shanghai University of Traditional Chinese Medicine, b.Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery,
Shanghai , China |
| Hong‑Xi Xuab |
a.School of Pharmacy, Shanghai University of Traditional Chinese Medicine, b.Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery,
Shanghai , China |
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| Abstract: |
| Herbal medicines, including traditional Chinese medicines (TCMs), have been used in Eastern countries for treating diseases such as cancer
for thousands of years. With the growing knowledge of tumorigenesis and cancer therapy, some natural compounds have been developed as
clinical anticancer drugs. In addition, many compounds and TCMs have been characterized as complementary and alternative treatments,
with synergetic effects on enhancing the efficacy or reducing the side effects of the therapeutics. In this review, we summarized the recent
studies focusing on the combination of natural compounds or TCM decoction with chemotherapeutics. The detailed mechanisms of action of
the combinations and the application of analytical methods on TCM development are also discussed. |
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