Investigation of Radix Achyranthis Bidentatae Phytochemistryand Pharmacology

Liu Yang<sup>a</sup>; A-Jiao Hou<sup>a</sup>; Mei-Ling Yan<sup>a</sup>; Xu-Dong Xing<sup>a</sup>; Xin-Yue Guo<sup>a</sup>; Hai Jiang<sup>a</sup>; Bing-You Yang<sup>a</sup>; Kelvin Chan<sup>cd</sup>; Qiu-Hong Wang<sup>ab</sup>; Hai-Xue Kuang<sup>a</sup>

Investigation of Radix Achyranthis Bidentatae Phytochemistryand Pharmacology

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KeyWord:Pharmacology, phytoecdysones, polysaccharides, radix achyranthis bidentatae, triterpenoid saponins

Author	Institution
Liu Yang^a	a. Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
A-Jiao Hou^a	a.Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
Mei-Ling Yan^a	a.Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
Xu-Dong Xing^a	a. Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
Xin-Yue Guo^a	a.Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
Hai Jiang^a	a.Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
Bing-You Yang^a	a.Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin
Kelvin Chan^cd	c.Centre for Complementary Medicine Research and;d.Faculty of Pharmacy, The University of Sydney, NSW, Australia
Qiu-Hong Wang^ab	a.Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin;b.School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China,
Hai-Xue Kuang^a	a. Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin

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Abstract:

Radix achyranthis bidentatae (RAB), a member of the Amaranthaceae family, has been widely used in Traditional Chinese Medicine for 1000s of years. Increasing interest in RAB-derived medicinal has led to the discovery of additional triterpenoid saponins, phytoecdysones, polysaccharides, and many other compounds, as well as investigations into their pharmacology. A large number of pharmacological studies have shown RAB and its active components possess a range of pharmacological activities, including anti-tumor, anti-fertility, anti-senile, and anti-inflammatory effects. This review is an up-to-date summary and synthesis of the uses of RAB from phytochemical and pharmacological perspectives.