|
| Traditional Chinese Medicine Syndromes Distribution in Colorectal Cancer and its Association with Western Medicine Treatment and Clinical Laboratory Indicators |
| |
| View Full Text View/Add Comment Download reader |
| DOI：10.4103/wjtcm.wjtcm_26_18 |
| KeyWord:Clinical laboratory indicators, colorectal cancer, traditional Chinese medicine syndrome distribution, treatment methods |
| Author | Institution |
| Meng-Die Yanga |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine |
| Xiao-Le Chena |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional
Chinese Medicine |
| Xue-Qing Huab |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine;b.Department of Oncology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine |
| Xiao-Zheng Xiea |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine |
| Wen-Jun Zhoua |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine |
| Chun-Gen Zhouc |
c.Department of Anorectal, Nanjing Hospital of Traditional Chinese Medicine, Nanjing |
| Bin Jiangc |
c.Department of Anorectal, Nanjing Hospital of Traditional Chinese Medicine, Nanjing |
| Qing Jiab |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine;b.Department of Oncology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine |
| Qi Lib |
b.Department of Oncology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine |
| Peng Wangd |
d.Department of Integrated
Traditional Chinese and Western Medicine, Tumour Hospital Affiliated to Fudan University |
| Zhi-Qiang Mengd |
d.Department of Integrated
Traditional Chinese and Western Medicine, Tumour Hospital Affiliated to Fudan University |
| Wen-Hai Wange |
e.Department of Proctology, Nanjing Hospital of Traditional Chinese Medicine |
| Yuan-Jia Huf |
f.Department of Integrated Traditional Chinese and Western Medicine, Tumour
Hospital Affiliated to Fudan University, Shanghai, China |
| Shi-Bing Sua |
a.Research Center for Traditional Chinese Medicine Complexity System, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine |
|
| Hits: 952 |
| Download times: 1061 |
| Abstract: |
| Objective: The objective of the study is to explore the traditional Chinese medicine (TCM) syndrome distribution in colorectal cancer (CRC)
and its correlation with treatment methods and clinical laboratory indicators. Materials and Methods: Using the CRC cases report form of
TCM, 760 CRC patients with TCM four diagnosis information, western medicine treatment information and clinical laboratory indicators were
collected, and TCM syndromes distribution in CRC were summarized. The correlation between TCM syndrome type and western medicine
treatments, clinical laboratory indicators such as liver and kidney function, immune function, and tumor biomarkers was analyzed. Results: In
760 cases of CRC, Spleen deficiency syndrome (SDS, 25%), liver and kidney Yin deficiency syndrome (LKYDS, 13%), LKYDS‑SDS,
12%, spleen deficient Qi stagnation syndrome (SDQSS, 10%), and damp heat syndrome (DHS, 9%) were more common TCM syndrome
types. LKYDS, SDS, LKYDS‑SDS, and SDQSS were significantly distributed under different treatment methods (P < 0.001). There was
no statistically significant difference in the distribution of immune function and cytokine among the five TCM syndromes (P > 0.05), but
there was statistically significant difference in the distribution of blood routine, liver and kidney function, and tumor biomarkers (P < 0.05).
Conclusion: LKYDS, SDS, LKYDS‑SDS, SDQSS, and DHS were the first five TCM syndromes in CRC. There were the significant
correlations between the distribution of TCM syndrome and the clinical laboratory indicators, and the distribution of TCM syndromes was
affected by surgery, radiotherapy, and chemotherapy |
| Close |
|
|
|